Amyloid arthropathy presenting as symmetrical polyarthritis

Tuberculosis presenting as polyarthritis.

A 34 years female was referred with a history of intermittent low to high grade fever with characteristic evening rise alongwith joint pains. There was symmetrical involvement of both small and largejoints of the body overthe preceding 6 months, with deterioration over preceding month so much so that she could not walk and became bed bound. The patient reported that her joints were stiff on wak...

Amyloid arthropathy associated with multiple myeloma: polyarthritis without synovial infiltration of CD20+ or CD38+ cells

OBJECTIVES To describe histological, immunohistochemical and ultrastructural features of synovial biopsies of amyloid arthropathy associated with multiple myeloma (MM). METHODS Synovial biopsies from affected joints of two patients with MM and amyloid arthropathy were examined with light and electron microscopy, and immunohistochemically for expression of CD3, CD8, CD20, CD38, CD68, Ki-67 and...

Eosinophilic fasciitis presenting as psoriatic arthropathy.

CASE HISTORY. A 19-year-old student nurse presented with a four month history of pain and stiffness in her knees, ankles and elbows following a brief 'flu-like illness. Wrist and elbow movements were limited, with bilateral knee effusions and flexion deformities of approximately 100. Evidence of psoriasis was limited to areas of hyperkeratosis on the elbows, and a few nail pits; there was a pos...

Symmetrical polyarthritis is not always rheumatoid.

Investigating symmetrical polyarthritis of recent origin.

was self limiting in 40-50% of cases. Polyarticular onset and small joint involvement (box) consistently predicted an unfavourable outcome. Full blood count, erythrocyte sedimentation rate, C reactive protein, and anticyclic citrullinated peptide (anti-CCP) (or rheumatoid factor) help in confirming a diagnosis of rheumatoid arthritis and indicating the likely prognosis. Other antibodies such as...